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Madoka Yoshida Selected Research

Acrolein (Aqualin)

8/2020Development of an ELISA for Measurement of Urinary 3-Hydroxypropyl Mercapturic Acid (3-HPMA), the Marker of Stroke.
6/2017Time dependent transition of the levels of protein-conjugated acrolein (PC-Acro), IL-6 and CRP in plasma during stroke.
1/2017Correlation between brain damage, associated biomarkers, and medication in psychiatric inpatients: A cross-sectional study.
10/2015Evaluation of dementia by acrolein, amyloid-β and creatinine.
2/2015Distinguishing mild cognitive impairment from Alzheimer's disease with acrolein metabolites and creatinine in urine.
3/2014Distinction between mild cognitive impairment and Alzheimer's disease by CSF amyloid β40 and β42, and protein-conjugated acrolein.
4/2012Inverse correlation between stroke and urinary 3-hydroxypropyl mercapturic acid, an acrolein-glutathione metabolite.
2/2012Augmented glutathione synthesis decreases acrolein toxicity.
1/2012Increased protein-conjugated acrolein and amyloid-β40/42 ratio in plasma of patients with mild cognitive impairment and Alzheimer's disease.
1/2011Relationship between metabolic disorders and relative risk values of brain infarction estimated by protein-conjugated acrolein, IL-6 and CRP together with age.
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Madoka Yoshida Research Topics

Disease

8Brain Infarction
06/2017 - 04/2009
7Stroke (Strokes)
08/2020 - 04/2009
4Cognitive Dysfunction
10/2015 - 01/2012
4Alzheimer Disease (Alzheimer's Disease)
10/2015 - 01/2012
3Dementia (Dementias)
10/2015 - 01/2014
2Infarction (Infarctions)
06/2017 - 01/2011
2Hemorrhage
06/2017 - 08/2008
2Carcinoma (Carcinomatosis)
02/2012 - 01/2009
2Carotid Artery Diseases
01/2011 - 08/2010
1Hemorrhagic Stroke
06/2017
1Mood Disorders (Mood Disorder)
01/2017
1Schizophrenia (Dementia Praecox)
01/2017
1Atrophy
01/2014
1Neuroblastoma
02/2012
1Thrombosis (Thrombus)
01/2011
1Chronic Kidney Failure (Chronic Renal Failure)
01/2010
1Vitreous Hemorrhage
08/2008
1Retinal Diseases
05/2007
1Central Nervous System Diseases (CNS Diseases)
05/2007
1Macular Degeneration (Age-Related Maculopathy)
12/2006
1Hypothermia
04/2006
1Papilledema
07/2003

Drug/Important Bio-Agent (IBA)

16Acrolein (Aqualin)IBA
08/2020 - 01/2009
10Proteins (Proteins, Gene)FDA Link
06/2017 - 01/2010
8Biomarkers (Surrogate Marker)IBA
06/2017 - 04/2009
5Interleukin-6 (Interleukin 6)IBA
06/2017 - 04/2009
3Acetylcysteine (Siran)FDA LinkGeneric
08/2020 - 04/2012
3Amyloid (Amyloid Fibrils)IBA
10/2015 - 01/2012
3CreatinineIBA
10/2015 - 04/2012
3hydroxypropyl methacrylateIBA
10/2015 - 04/2012
3Reactive Oxygen Species (Oxygen Radicals)IBA
02/2012 - 01/2009
2Glutathione (Reduced Glutathione)IBA
08/2020 - 04/2012
2Oxidoreductases (Dehydrogenase)IBA
04/2012 - 04/2009
1C-Reactive ProteinIBA
01/2017
1Antipsychotic Agents (Antipsychotics)IBA
01/2017
1Biological ProductsIBA
10/2015
1Pemetrexed (MTA)FDA Link
01/2014
1EnzymesIBA
04/2012
1PolyaminesIBA
04/2012
1Phospholipids (Phosphatides)FDA LinkGeneric
01/2011
1DNA (Deoxyribonucleic Acid)IBA
01/2011
1AlbuminsIBA
01/2011
1RNA (Ribonucleic Acid)IBA
01/2011
1Polyamine OxidaseIBA
04/2009
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
08/2008
1Complement Factor H (Factor H)IBA
12/2006
1Trypan BlueFDA Link
04/2006
1Retinal Pigments (Pigments, Visual)IBA
04/2006
1Coloring Agents (Dyes)IBA
07/2003
1Retinaldehyde (Retinal)IBA
07/2003
1Fluorescein (Funduscein)FDA LinkGeneric
07/2003

Therapy/Procedure

1Transplantation
05/2007